![](/__local/6/1A/8D/E731F469C2CF0162F960DA680A6_8E30875F_45AEF.png)
魏小东,博士,“西部之光访问学者”
职称:副教授,专业:药学
联系方式
E-mail:wxdswu@163.com
教育与工作经历
2020.11--至今 天水师范学院,讲师
2021.09-2022.07 “西部之光”访问学者
2017.09-2020.06 西南大学,药学院,博士
研究方向
1.中药及天然药物活性成分研究:利用色谱法从中药提取、分离活性成分,利用NMR、MS等方法解析化合物结构。
2.药理学研究:对活性成分肝保护及抗肿瘤等作用及机制研究。
承担课题
1.甘肃省自然基金项目(2022.10-2024.09, 22JR5RE198)
2.甘肃省高等学校创新基金项目(2021.06-2023.06, 2021B-210)
3.天水师范学院高级别预研项目(2022.01-2022.12, G**2021-07)
4.中央高校业务费学生项目(2019.06-2020.06, XDJK2019D037)
论文发表
1.Wei XD, Ma YX, Dong ZY, et al. Dehydrodiconiferyl alcohol, a lignan from Herpetospermum pedunculosum, alleviates cholestasis by activating pathways associated with the farnesoid X receptor. Phytomedicine. 2021, 153378.(IF=6.65)
2.Wei XD, Fan XD, Feng ZY, et al. Ethyl acetate extract of Herpetospermum pedunculosum alleviates α-naphthylisothiocyanate-induced cholestasis by activating the farnesoid X receptor and suppressing oxidative stress and inflammation in rats. Phytomedicine. 2020, 153257.(IF=6.65)
3. Wei XD*, Zeng YP, Meng FC, et al. Calycosin-7-glucoside promotes mitochondria-mediated apoptosis in hepatocellular carcinoma by targeting thioredoxin 1 to regulate oxidative stress. Chemico-Biological Interactions. 2023, 110411.(IF=5.17)
4.Wei XD*, Zeng YP, Sun C, Meng FC, et al. Recent advances in natural phthalides: Distribution, chemistry, and biological activities. Fitoterapia. 2022, 105223.(IF=3.20)
5.Wei XD, Shen HL, Wang LJ, et al. Analyses of Total Alkaloid Extract of Corydalis yanhusuo by Comprehensive RP × RP Liquid Chromatography with pH Difference. Journal of Analytical Methods in Chemistry. 2016.(IF=2.60)